USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P68363 USC-OGP 2-DE database:  P68363 P68363 General information about the entry View entry in simple text format Entry name TBA1B_HUMAN Primary accession number P68363 Secondary accession number(s) P04687 P05209 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Tubulin alpha-1B chain; AltName: Full=Alpha-tubulin ubiquitous; AltName: Full=Tubulin K-alpha-1; AltName: Full=Tubulin alpha-ubiquitous chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1B chain;. Gene name Name=TUBA1B Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0237: pI=5.02; Mw=18707 SPOT OGP-0238: pI=4.98; Mw=18582 PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0356: pI=5.04; Mw=51842 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0662: pI=5.03; Mw=52994 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1201: pI=5.96; Mw=39564 Cross-references UniProtKB/Swiss-Prot P68363; TBA1B_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TBA1B_HUMAN Primary accession number P68363 Secondary accession number(s) P04687 P05209 Q27I68 Q8WU19 Sequence was last modified on  August 13, 1987 (version 1) Annotations were last modified on  March 15, 2017 (version 143) Name and origin of the protein Description RecName: Full=Tubulin alpha-1B chain; AltName: Full=Alpha-tubulin ubiquitous; AltName: Full=Tubulin K-alpha-1; AltName: Full=Tubulin alpha-ubiquitous chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1B chain; Gene name Name=TUBA1B Encoded on Name=TUBA1B Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTP-binding; Isopeptide bond; Methylation; Microtubule; Nitration; Nucleotide-binding; Phosphoprotein; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL K00558; AAA91576.1; -; mRNA EMBL AF081484; AAC31959.1; -; mRNA EMBL DQ400107; ABD60581.1; -; mRNA EMBL BC000696; AAH00696.1; -; mRNA EMBL BC001128; AAH01128.1; -; mRNA EMBL BC006379; AAH06379.1; -; mRNA EMBL BC006481; AAH06481.1; -; mRNA EMBL BC008659; AAH08659.1; -; mRNA EMBL BC009314; AAH09314.1; -; mRNA EMBL BC009509; AAH09509.1; -; mRNA EMBL BC009512; AAH09512.1; -; mRNA EMBL BC009513; AAH09513.1; -; mRNA EMBL BC010494; AAH10494.1; -; mRNA EMBL BC011572; AAH11572.1; -; mRNA EMBL BC015883; AAH15883.1; -; mRNA EMBL BC017004; AAH17004.1; -; mRNA EMBL BC021564; AAH21564.1; -; mRNA EMBL BC030820; AAH30820.1; -; mRNA EMBL BC071904; AAH71904.1; -; mRNA CCDS CCDS31792.1; -. [P68363-1]; . PIR I77403; I77403; . RefSeq NP_006073.2; NM_006082.2. [P68363-1]; . UniGene Hs.524390; -; . PDB 2E4H; NMR; -; B=416-451 PDB 5IJ0; EM; 3.80 A; A=1-437 PDB 5IJ9; EM; 3.70 A; A=1-437 PDBsum 2E4H; -; . PDBsum 5IJ0; -; . PDBsum 5IJ9; -; . ProteinModelPortal P68363; -; . SMR P68363; -; . BioGrid 115651; 124; . IntAct P68363; 40; . MINT MINT-4998849; -; . STRING 9606.ENSP00000336799; -; . ChEMBL CHEMBL2095182; -; . DrugBank DB05147; CYT997; . DrugBank DB03010; Epothilone B; . DrugBank DB01873; Epothilone D; . iPTMnet P68363; -; . PhosphoSitePlus P68363; -; . SwissPalm P68363; -; . BioMuta TUBA1B; -; . DMDM 55977474; -; . OGP P68363; -; . SWISS-2DPAGE P68363; -; . EPD P68363; -; . MaxQB P68363; -; . PaxDb P68363; -; . PeptideAtlas P68363; -; . PRIDE P68363; -; . TopDownProteomics P68363-1; -. [P68363-1]; . DNASU 10376; -; . Ensembl ENST00000336023; ENSP00000336799; ENSG00000123416. [P68363-1]; . GeneID 10376; -; . KEGG hsa:10376; -; . UCSC uc001rtm.4; human. [P68363-1]; . CTD 10376; -; . DisGeNET 10376; -; . GeneCards TUBA1B; -; . H-InvDB HIX0079488; -; . HGNC HGNC:18809; TUBA1B; . HPA CAB011513; -; . HPA HPA039247; -; . HPA HPA043684; -; . HPA HPA063394; -; . MIM 602530; gene; . neXtProt NX_P68363; -; . OpenTargets ENSG00000123416; -; . PharmGKB PA162407332; -; . eggNOG KOG1376; Eukaryota; . eggNOG COG5023; LUCA; . GeneTree ENSGT00870000136497; -; . HOGENOM HOG000165711; -; . HOVERGEN HBG000089; -; . InParanoid P68363; -; . KO K07374; -; . OMA WARTRNT; -; . OrthoDB EOG091G0736; -; . PhylomeDB P68363; -; . TreeFam TF300314; -; . Reactome R-HSA-1445148; Translocation of GLUT4 to the plasma membrane; . Reactome R-HSA-190840; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; . Reactome R-HSA-190861; Gap junction assembly; . Reactome R-HSA-2132295; MHC class II antigen presentation; . Reactome R-HSA-2467813; Separation of Sister Chromatids; . Reactome R-HSA-2500257; Resolution of Sister Chromatid Cohesion; . Reactome R-HSA-380320; Recruitment of NuMA to mitotic centrosomes; . Reactome R-HSA-389960; Formation of tubulin folding intermediates by CCT/TriC; . Reactome R-HSA-389977; Post-chaperonin tubulin folding pathway; . Reactome R-HSA-437239; Recycling pathway of L1; . Reactome R-HSA-5610787; Hedgehog 'off' state; . Reactome R-HSA-5617833; Cilium Assembly; . Reactome R-HSA-5620924; Intraflagellar transport; . Reactome R-HSA-5626467; RHO GTPases activate IQGAPs; . Reactome R-HSA-5663220; RHO GTPases Activate Formins; . Reactome R-HSA-6807878; COPI-mediated anterograde transport; . Reactome R-HSA-6811434; COPI-dependent Golgi-to-ER retrograde traffic; . Reactome R-HSA-6811436; COPI-independent Golgi-to-ER retrograde traffic; . Reactome R-HSA-68877; Mitotic Prometaphase; . Reactome R-HSA-8852276; The role of GTSE1 in G2/M progression after G2 checkpoint; . Reactome R-HSA-983189; Kinesins; . SIGNOR P68363; -; . ChiTaRS TUBA1B; human; . EvolutionaryTrace P68363; -; . GeneWiki TUBA1B; -; . GenomeRNAi 10376; -; . PRO PR:P68363; -; . Proteomes UP000005640; Chromosome 12; . Bgee ENSG00000123416; -; . CleanEx HS_TUBA1B; -; . ExpressionAtlas P68363; baseline and differential; . Genevisible P68363; HS; . GO GO:0005881; C:cytoplasmic microtubule; IEA:Ensembl; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005874; C:microtubule; IDA:UniProtKB; . GO GO:0015630; C:microtubule cytoskeleton; IDA:HPA; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0003725; F:double-stranded RNA binding; IDA:MGI; . GO GO:0005525; F:GTP binding; IEA:UniProtKB-KW; . GO GO:0003924; F:GTPase activity; IEA:InterPro; . GO GO:0005200; F:structural constituent of cytoskeleton; IEA:Ensembl; . GO GO:0005198; F:structural molecule activity; TAS:BHF-UCL; . GO GO:0031625; F:ubiquitin protein ligase binding; IPI:ParkinsonsUK-UCL; . GO GO:0051301; P:cell division; TAS:BHF-UCL; . GO GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl; . GO GO:0030705; P:cytoskeleton-dependent intracellular transport; TAS:BHF-UCL; . GO GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl; . GO GO:0007017; P:microtubule-based process; TAS:BHF-UCL; . Gene3D 1.10.287.600; -; 1; . Gene3D 3.30.1330.20; -; 1; . Gene3D 3.40.50.1440; -; 1; . InterPro IPR002452; Alpha_tubulin; . InterPro IPR008280; Tub_FtsZ_C; . InterPro IPR000217; Tubulin; . InterPro IPR018316; Tubulin/FtsZ_2-layer-sand-dom; . InterPro IPR023123; Tubulin_C; . InterPro IPR017975; Tubulin_CS; . InterPro IPR003008; Tubulin_FtsZ_GTPase; . PANTHER PTHR11588; PTHR11588; 1; . Pfam PF00091; Tubulin; 1; . Pfam PF03953; Tubulin_C; 1; . PRINTS PR01162; ALPHATUBULIN; . PRINTS PR01161; TUBULIN; . SMART SM00864; Tubulin; 1; . SMART SM00865; Tubulin_C; 1; . SUPFAM SSF52490; SSF52490; 1; . SUPFAM SSF55307; SSF55307; 1; . PROSITE PS00227; TUBULIN; 1; .

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